CommercialPrior AuthHigh impact
Medical Policy Updates for November 2026
Blue Cross Blue Shield of Massachusetts·MA · Pharmacy, Endocrinology, Pulmonology +5 more·Medical Policy
Effective date
Sep 15, 2026
We identified it
Aug 1, 2026
Summary
Blue Cross Blue Shield of Massachusetts has updated 10 pharmacy policies and Carelon medical guidelines effective September 15, 2026, with an additional genetic testing guideline update effective August 22, 2026. All pharmacy policy changes require prior authorization for commercial plans, affecting medications across immune modulation, lipid management, asthma, diabetes, cancer support, and rare disease categories. Billing teams must implement prior authorization requirements in their systems and educate providers on new step therapy requirements for diabetes medications.
Action Required
By September 1, 2026: Billing team must update all billing software and clearinghouse settings to require prior authorization for the following pharmacy policies effective September 15, 2026: Policy 004 (Immune Modulating Drugs - Skyrizi, Xeljanz), Policy 013 (Anti-Hyperlipidemics - Repatha, Praluent, Leqvio, Lerochol, Tyngolza), Policy 017 (Injectable Asthma - Exdensur, Fasenra), Policy 033 (MED UM & Pharmacy - Forzinity, Osvyrti, Jubereq), Policy 041 (Diabetes Step Therapy - generic Januvia and Janumet now require Step 2 therapy), Policy 049 (Drug Management - Jascayd, Palsonify), Policy 093 (Complement disorders - Vyvgart/Vyvgart Hytrulo), Policy 105 (Cancer supportive care - Armlupeg, Filkri), and Policy 346 (Ophthalmic - Rescula removed from market, no longer billable). Providers and staff must be notified of new step therapy requirements for diabetes medications. Update all prior authorization submission processes and encounter forms. Claims submitted without required prior authorization will be denied. Additionally, by August 22, 2026, update system alerts regarding Category III CPT codes to reflect that all 2026 Category III codes are non-covered unless explicitly listed as medically necessary in a BCBSMA policy—staff must verify coverage via https://www.bluecrossma.org/medical-policies/ before billing.