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11.05.01h, Refractive Keratoplasty, Keratoprosthesis, and Corneal Collagen Cross-Linking

Independence Blue Cross·Ophthalmology·Medical Policy
Effective date
Jul 27, 2026
We identified it
Jul 28, 2026
Days to comply
—

Summary

Independence Blue Cross expanded policy 11.05.01h to include Keratoprosthesis and Corneal Collagen Cross-Linking coverage criteria. Corneal collagen cross-linking epithelium-off is now covered for progressive keratoconus and corneal ectasia post-refractive surgery, while epithelium-on procedures remain experimental/investigational. Boston KPro keratoprosthesis coverage criteria are detailed with specific visual acuity and clinical requirements.

Action Required

Action needed
By July 27, 2026: (1) Billing team must update claim submission system to recognize CPT 0402T as covered ONLY when supporting diagnosis codes document progressive keratoconus (H18.601, H18.602, H18.603, H18.609) or corneal ectasia post-refractive surgery; all other uses deny as experimental/investigational. (2) Update system to deny CPT 0402T claims if procedure is documented as epithelium-on technique; only epithelium-off is covered. (3) For CPT 65770 (Boston KPro), require prior authorization verification that patient meets ALL criteria: (a) cadaveric transplant failure/low success likelihood, (b) severe opaque/vascularized cornea, (c) best-corrected visual acuity ≤20/400 affected eye AND ≤20/40 contralateral eye, (d) no end-stage glaucoma/retinal detachment, (e) qualifying indication (prior graft failure, Stevens-Johnson, OCP, chemical burn, etc.). (4) Deny all other keratoprosthesis devices (not Boston KPro) as experimental/investigational. (5) Verify all refractive keratoplasty claims (CPT 65772, 65775, 66999) document astigmatism correction from trauma or prior eye surgery only; deny cosmetic/refractive error cases. (6) Continue denying LASIK/PRK/PTK (HCPCS S0800, S0810, S0812) and radial keratotomy (CPT 65771) as not eligible. Providers must obtain documentation supporting medical necessity before claim submission or claims will be denied.

Affected Billing Codes

65770
65772
65775
66999
65760
65765
65767
65771
C1818
L8609
S0800
S0810
S0812