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CommercialCoverageMedium impact

Prolotherapy 8.01.10

Excellus BlueCross BlueShield·Orthopedics, Pain Management, Sports Medicine +2 more·Bone & Joints (Orthopedic)
Effective date
Oct 15, 2025
We identified it
Jul 16, 2026
Days to comply

Summary

Excellus BlueCross BlueShield has classified Prolotherapy (8.01.10) as investigational for treating musculoskeletal pain and instability, effective October 15, 2025. This means prolotherapy procedures will not be covered and claims will be denied unless the member's contract specifically includes coverage for investigational services. Billing teams must implement denial protocols and update systems to route prolotherapy claims appropriately.

Action Required

Action needed
By October 15, 2025: Billing team must (1) Update billing system to flag all prolotherapy procedure submissions as investigational/non-covered for Excellus BlueCross BlueShield plans; (2) Review member contracts to identify any exceptions that include investigational service coverage; (3) Implement denial protocol for prolotherapy claims—claims will be automatically denied under investigational services policy (reference corporate policy 11.01.03); (4) Notify providers in orthopedic, pain management, and sports medicine departments of the coverage change via encounter form updates and staff communication; (5) Update patient billing statements and explanation of benefits templates to reference investigational status; (6) Train front desk and authorization staff to inform patients that prolotherapy is non-covered and may require patient self-pay or prior verification of any plan exceptions. Failure to implement denial protocols will result in improper claim payments and potential recovery issues.