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Excellus BlueCross BlueShieldCommercial · Coverage · Bone & Joints (Orthopedic) · NY · OrthopedicsMedium impact

Autologous Chondrocyte Implantation (ACI) - (Effective Date - 2026-10-15) 7.01.38

Effective date
Oct 15, 2026
Identified
Jul 16, 2026

Summary

Excellus BlueCross BlueShield medical policy 7.01.38 on autologous chondrocyte implantation (ACI), using the matrix-induced ACI (MACI) implant, has a current effective date of October 15, 2026. ACI is considered medically appropriate for individuals aged 15 to 55 with a BMI of 35 or less, no inflammatory arthritis, Kellgren-Lawrence Grade II or less on radiographs, and a full-thickness distal femoral or patellar chondral defect of 1 to 10 cm2 identified by CT arthrogram, by MRI with Modified Outerbridge Grade III or IV, or by arthroscopy with Outerbridge Grade III or IV. The policy also requires function-limiting knee pain and at least three months of failed provider-directed, non-surgical management, and it considers ACI not medically necessary for several other indications, including any knee joint surgery within six months before screening and cruciate ligament instability. Hybrid ACI performed with osteochondral autograft transfer is considered investigational for osteochondral defects.

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What to do

Action · 8 steps
01Already effective October 15, 2026: Billing team should confirm that the chart supports every criterion before billing ACI (CPT 27412) and the implant (HCPCS J7330).
02The chart needs documentation that the individual is 15 to 55 years old with a BMI of 35 or less, has no inflammatory arthritis or other systemic joint disease, and has Kellgren-Lawrence Grade II or less on radiographs.
03The chart also needs documentation of a full-thickness distal femoral or patellar defect of 1 to 10 cm2 identified by CT arthrogram, by MRI with Modified Outerbridge Grade III or IV, or by arthroscopy with Outerbridge Grade III or IV, with normal articular cartilage at the lesion border.
04The exam needs to show a stable knee with intact or reconstructed ligaments and menisci (a concurrent ligament stabilization or meniscal procedure at the time of ACI is acceptable) and normal tibial-femoral or patella-femoral alignment.
05The chart needs documentation of function-limiting knee pain or loss of knee function that interferes with age-appropriate activities of daily living, and of at least three months of failed provider-directed, non-surgical management.
06For femoral and patellar lesions, the chart must show no osteochondritis dissecans lesion that requires bone grafting and no corresponding Modified Outerbridge Grade III or IV kissing lesion.
07Claims need to show no knee joint surgery within six months before screening (except a biopsy or a concomitant procedure to prepare the knee for a MACI implant), no septic arthritis within one year before screening, no known hypersensitivity to gentamicin, other aminoglycosides, or porcine or bovine products, no uncorrected congenital blood coagulation disorder, and no cruciate ligament instability.
08Hybrid ACI with osteochondral autograft transfer is investigational for osteochondral defects.

Codes mentioned

27412J7330S2112M12.561M12.569M17.0M17.9M23.50M23.52M23.8X1M23.8X9M23.90M23.92M25.261M25.269M25.361M25.369M25.861M25.869M85.9M89.8X6M89.9M93.20M93.261M93.269M94.8X6M94.9

Original notice

Autologous Chondrocyte Implantation (ACI) - (Effective Date - 2026-10-15) 7.01.38
excellusbcbs.com · Always check the source before changing claims.
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