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Medicare AdvantagePrior AuthHigh impact

Drug Management Program-Opioid Program (Revised)

Humana·Pharmacy, Pain Management, Psychiatry +1 more·Pharmacy
Effective date
Jul 23, 2025
We identified it
Jun 25, 2026
Days to comply

Summary

Humana revised its Drug Management Program-Opioid Program (effective July 23, 2025) to strengthen beneficiary-level edits for at-risk opioid and benzodiazepine users on Medicare. The policy now includes refined criteria for triggering reviews (MME thresholds, prescriber/pharmacy counts, overdose history), specific exclusions (cancer, hospice, palliative care, long-term care, assisted living, sickle cell), and clear procedures for adjustment or removal of restrictions. Billing teams must implement these changes to ensure compliant pharmacy claim processing and avoid claim denials for members subject to quantity limits or prescriber/pharmacy restrictions.

Action Required

Action needed
By July 23, 2025: Billing and pharmacy teams must immediately implement the revised Drug Management Program-Opioid Program edits in all claims processing systems. REQUIREMENTS: (1) Update point-of-sale (POS) system to enforce new beneficiary-level edits based on revised MME thresholds (90 mg average daily) and prescriber/pharmacy count criteria (3+ prescribers AND 3+ pharmacies, OR 5+ prescribers); (2) Configure system to apply MME dose limits, prescriber restrictions, and pharmacy restrictions to flagged members after case management review; (3) Ensure system excludes specified products from MME calculations (buprenorphine excluded from MME but included in prescriber/pharmacy counts; opium tincture, cough/cold products, injectable opioids excluded from both); (4) Implement member exclusion workflows for cancer pain, hospice, palliative/end-of-life care, long-term care residents, assisted living facility residents (with single-pharmacy contract), and sickle cell patients—requiring prescriber attestation if not documented in Humana system; (5) Program edit durations as 12 months initial (extendable to 24 months if at-risk behavior continues); (6) Create processes for member/prescriber/pharmacy requests to adjust or remove restrictions, with documented justification (prescriber attestation, health condition changes, successful appeals); (7) Configure re-evaluation protocols if members reappear on Overutilization Monitoring System (OMS) reports after edit removal; (8) Train billing, claims, and prior authorization staff on new criteria and exemption requirements. CONSEQUENCES: Failure to implement will result in claim denials for members with active quantity/prescriber/pharmacy limits, member complaints for inappropriate claim rejections, and compliance violations with Humana's Medicare drug management requirements.