Medicare AdvantageBilling CodesLow impact
MA06.021d, In Vitro Chemosensitivity and Chemoresistance Assays
Independence Blue Cross·NJ · Oncology, Pathology·Medical Policy
We identified it
Jun 25, 2026
Summary
Independence Blue Cross has reissued MA06.021d with no substantive changes to coverage policy. In vitro chemosensitivity and chemoresistance assays remain non-covered (experimental/investigational) for Medicare Advantage members. Two procedure codes—0564T and 81536—have been added to the policy documentation.
Action Required
No immediate billing changes required. The reissued policy confirms continued non-coverage of in vitro chemosensitivity and chemoresistance assays. Billing staff should ensure claims for CPT codes 0564T, 81535, 81536, and 89240 submitted to Independence Blue Cross Medicare Advantage plans are denied with the rationale 'experimental/investigational service—not covered.' Update internal reference materials to reflect the added codes (0564T and 81536) in the policy documentation if tracking code-specific denials. No prior authorization process exists for these services as they are excluded benefits.