Signifor® LAR (pasireotide) (Revised)

Immediately: Billing team must implement prior authorization process for all Signifor LAR (pasireotide) injection claims for Kentucky and South Carolina Medicaid members. Providers must document diagnosis of Cushing's Disease or Acromegaly, inadequate response to pituitary surgery or surgery contraindications, and absence of severe hepatic impairment (Child-Pugh C). For Acromegaly cases with Medicare Part B, verify if continuation of prior therapy within 365 days to bypass step therapy requirements. Claims will be denied without proper prior authorization.