MedicaidCoverageMedium impact
Amtagvi (lifileucel) - MEDICAID - FLORIDA (New)
Humana·FL · Oncology·Medicaid
Effective date
Nov 5, 2025
We identified it
Jun 24, 2026
Summary
Humana Medicaid in Florida has established a new policy for coverage of Amtagvi (lifileucel), an autologous tumor-derived T cell immunotherapy for previously treated unresectable or metastatic melanoma. All requests require review by a medical director and must be referred to the Corporate Transplant Department.
Action Required
Before November 5, 2025: Billing team must update system to recognize new HCPCS codes C9399, J3490, J3590 and ICD-10-PCS codes XW033L7, XW043L7 for Amtagvi therapy. All requests must be referred to Corporate Transplant Department at 1-866-421-5663 or transplant@humana.com for medical director review before treatment. Update prior authorization workflows to require medical director approval for all Amtagvi claims.