Medicare AdvantagePrior AuthMedium impact
Topical Nystatin Powder (New)
Humana·Dermatology, Family Medicine, Internal Medicine +1 more·Medicare Advantage
Effective date
Jan 1, 2026
We identified it
Jun 24, 2026
Summary
Humana Medicare Advantage plans now require prior authorization for topical nystatin powder (Klayesta) effective January 1, 2026. Coverage requires the medication be used topically for active cutaneous or mucocutaneous candidiasis treatment.
Action Required
By January 1, 2026: Billing team must implement prior authorization requirements for topical nystatin powder (Klayesta) prescriptions for Humana Medicare Advantage members. Update pharmacy billing workflows to obtain prior auth before dispensing. Providers must document that medication is for topical treatment of active cutaneous or mucocutaneous candidiasis. Visit www.humana.com/PAL for specific medical coding requirements.