Medicare AdvantagePrior AuthMedium impact
Siklos (hydroxyurea) tablet (New)
Humana·Hematology, Oncology, Internal Medicine +2 more·Medicare Advantage
Effective date
Jan 1, 2026
We identified it
Jun 24, 2026
Summary
Humana Medicare Advantage now requires prior authorization for Siklos (hydroxyurea) tablets for sickle cell anemia patients, effective January 1, 2026. Patients must have tried both hydroxyurea capsule and L-glutamine oral packet before Siklos will be approved.
Action Required
By January 1, 2026: Billing team must update prior authorization workflows for Siklos (hydroxyurea) tablets for Medicare Advantage patients. Providers must document patient diagnosis of sickle cell anemia and previous treatment/intolerance with both hydroxyurea capsule AND L-glutamine oral packet before prescribing. Visit www.humana.com/PAL for medical and procedural coding information. Claims will be denied without proper prior authorization.