Medicare AdvantagePrior AuthLow impact
L-glutamine (Endari) oral powder packet (Revised)
Humana·Hematology, Oncology, Pediatrics +2 more·Medicare Advantage
Effective date
Jan 1, 2026
We identified it
Jun 24, 2026
Summary
Humana Medicare Advantage now requires prior authorization for L-glutamine (Endari) oral powder packets for sickle cell disease treatment, with specific criteria including 2+ crises in 12 months and prior hydroxyurea treatment history. This policy becomes effective January 1, 2026.
Action Required
Before January 1, 2026: Update prior authorization processes for L-glutamine (Endari) prescriptions for Humana Medicare Advantage members. Ensure documentation includes sickle cell disease diagnosis, 2+ crises in previous 12 months, and hydroxyurea treatment history. Train clinical staff on new authorization criteria to prevent claim denials.