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Medicare AdvantagePrior AuthMedium impact

Briviact® (brivaracetam) (Revised)

Humana·Neurology, Family Medicine, Internal Medicine +1 more·Medicare Advantage
Effective date
Jan 1, 2026
We identified it
Jun 24, 2026
Days to comply

Summary

Humana Medicare Advantage now requires prior authorization for Briviact (brivaracetam) for partial-onset seizures, with specific criteria requiring failure of levetiracetam plus at least one other anti-seizure medication. This policy is effective January 1, 2026 and covers all forms of the medication including tablets, oral solution, and IV solution.

Action Required

Action needed
Before January 1, 2026: Billing and clinical teams must implement prior authorization requirements for all Briviact (brivaracetam) prescriptions for Humana Medicare Advantage patients. Update system to verify patients have failed both levetiracetam AND at least one other anti-seizure medication (lamotrigine, carbamazepine, zonisamide, divalproex, gabapentin, or topiramate) before prescribing. Provider documentation must include diagnosis of partial-onset seizures and medication failure history. Claims will be denied without proper prior authorization.