MedicaidPrior AuthMedium impact
Oncaspar® (pegaspargase) (New)
Humana·LA · Oncology, Hematology, Pediatrics·Medicaid
Effective date
Feb 1, 2026
We identified it
Jun 24, 2026
Summary
Humana Louisiana Medicaid has implemented a new prior authorization policy for Oncaspar® (pegaspargase) effective February 1, 2026. Prior authorization is now required for this acute lymphoblastic leukemia (ALL) medication with specific approval criteria and exclusions that must be met.
Action Required
Before February 1, 2026: Billing team must ensure prior authorization is obtained for all Oncaspar (pegaspargase) prescriptions for Louisiana Medicaid patients with ALL diagnosis. Verify patient meets approval criteria (ALL diagnosis and multi-agent chemotherapy regimen) and does not have exclusionary conditions (disease progression, thrombosis history, pancreatitis history, hemorrhagic events history, or elevated bilirubin). Update workflow to submit prior auth requests with 6-month approval duration. Claims will be denied without prior authorization.