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MedicaidBilling CodesMedium impact

Esketamine Billing Instructions

South Dakota Medicaid·SD · Psychiatry·Pharmacy
Effective date
Jan 1, 2026
We identified it
Jun 21, 2026
Days to comply

Summary

South Dakota Medicaid is changing the HCPCS code for Esketamine (Spravato) nasal spray billing from S0013 to J0013 effective January 1, 2026. The policy clarifies specific E/M codes and add-on codes for associated professional services and observation time.

Action Required

Action needed
By January 1, 2026: Billing team must update system to use HCPCS code J0013 instead of S0013 for Esketamine (Spravato) nasal spray for South Dakota Medicaid. Continue using CPT 99205 for new patients, 99215 for established patients, and up to 6 units of 99417 for extended observation time. Ensure prior authorization is obtained before administration.

Affected Billing Codes

S0013
J0013
99205
99215
99417