CommercialBilling CodesMedium impact
Medical Policy Update for February 26, 2025
Blue Cross NC·NC · Pathology, Infectious Disease, Oncology +2 more·Medical Policy
Effective date
Feb 26, 2025
We identified it
Jun 16, 2026
Summary
Blue Cross NC updated multiple medical policies with billing code changes effective 1/1/2025 and February 2025. Key changes include removing codes 0346U and 0456U from certain policies, adding CPT 87626 to STI and oral cancer screening, and adding multiple PLA codes to pathogen panel testing.
Action Required
Immediately: Update billing system to remove deleted codes 0346U (Alzheimer biomarkers), 0456U (autoimmune rheumatic disease), and 0380U (pharmacogenetics). Add CPT 87626 to STI testing and oral cancer screening billing options. Add PLA codes 0202U, 0223U, and 0225U for pathogen panel testing. Add codes 87164 and 87166 for vector-borne infection testing. Verify all changes are reflected in encounter forms and billing software.