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Medicare AdvantagePrior AuthMedium impact

Updated Category for Medicare Advantage Part B Step Therapy

Florida Blue·FL · Oncology, Hematology·Medicare
Effective date
Oct 1, 2025
We identified it
Jun 16, 2026
Days to comply

Summary

Florida Blue Medicare updated its Part B Step Therapy program for colony-stimulating factors, adding several new non-preferred products that now require step therapy. Providers must try preferred alternatives (Fulphila, Udenyca, Nyvepria) before using the newly added non-preferred drugs.

Action Required

Action needed
By October 1, 2025: Providers must prescribe preferred colony-stimulating factors (Fulphila, Udenyca, Nyvepria) before non-preferred products. Billing team should update prior authorization workflows for the newly added non-preferred drugs (Fylnetra, Rolvedon, Stimufend, Ryzneuta, Nypozi, Ziextenzo). Update encounter forms and EMR templates to remind providers of step therapy requirements.

Affected Billing Codes

Q5108
Q5111
Q5122
J2506
Q5130
J1449
Q5127
J9361
Q5148
Q5120