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Handheld Radiofrequency Spectroscopy for Intraoperative Assessment of Surgical Margins During Breast-Conserving Surgery

Blue Cross & Blue Shield of Mississippi·General Surgery, Oncology·Medical Policy
Effective date
Not stated
We identified it
Jun 20, 2026
Days to comply

Summary

This policy confirms that handheld radiofrequency spectroscopy (MarginProbe) for intraoperative assessment of surgical margins during breast-conserving surgery remains investigational and non-covered. The policy was reviewed with no changes, maintaining the existing coverage determination.

Action Required

Action needed
No immediate action required. Continue to consider CPT code 0546T (radiofrequency spectroscopy for intraoperative margin assessment) and 19499 (unlisted breast procedure) as investigational/non-covered when used for handheld radiofrequency spectroscopy during breast-conserving surgery. Inform patients these procedures may not be covered.

Affected Billing Codes

19499