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Handheld Radiofrequency Spectroscopy for Intraoperative Assessment of Surgical Margins During Breast-Conserving Surgery
Blue Cross & Blue Shield of Mississippi·General Surgery, Oncology·Medical Policy
We identified it
Jun 20, 2026
Summary
This policy confirms that handheld radiofrequency spectroscopy (MarginProbe) for intraoperative assessment of surgical margins during breast-conserving surgery remains investigational and non-covered. The policy was reviewed with no changes, maintaining the existing coverage determination.
Action Required
No immediate action required. Continue to consider CPT code 0546T (radiofrequency spectroscopy for intraoperative margin assessment) and 19499 (unlisted breast procedure) as investigational/non-covered when used for handheld radiofrequency spectroscopy during breast-conserving surgery. Inform patients these procedures may not be covered.