CommercialCoverageMedium impact
Genetic Testing for Predisposition to Inherited Hypertrophic Cardiomyopathy
Blue Cross & Blue Shield of Mississippi·MS · Cardiology, Family Medicine, Internal Medicine·Medical Policy
We identified it
Jun 20, 2026
Summary
BCBS Mississippi updated their medical policy for genetic testing for hypertrophic cardiomyopathy predisposition. The policy establishes that genetic testing is medically necessary for individuals with a first-degree relative who has established hypertrophic cardiomyopathy and a known pathogenic gene variant, but is investigational (not covered) when the relative tested negative for pathogenic variants.
Action Required
Immediately: Billing team must verify family history and genetic testing results before submitting claims for hypertrophic cardiomyopathy genetic testing. Ensure documentation shows patient has first-degree relative with established hypertrophic cardiomyopathy AND that relative has known pathogenic gene variant. Claims will be denied if relative tested negative for pathogenic variants or if proper family history documentation is missing.