Blue Cross & Blue Shield of MississippiCommercial · Prior Auth · Medical Policy · MS · Endocrinology, Pediatrics, GeneticsLow impact
Strensiq (asfotase alfa)
Act
by Jun 1, 2025
Effective date
Jun 1, 2025
Identified
Jun 20, 2026
Summary
BCBS Mississippi updated their prior authorization policy for Strensiq (asfotase alfa), a rare disease medication for hypophosphatasia, with revised medical necessity criteria and new renewal requirements effective June 1, 2025.
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01Update prior authorization protocols for Strensiq (asfotase alfa) to reflect new medical necessity criteria requiring ophthalmology examination and renal ultrasound at baseline, active disease documentation, and clinical manifestations prior to age 18.
02Update renewal criteria to require documented clinical improvement in respiratory status, growth, radiographic findings, or activity level.
03Train staff on revised criteria as this affects rare pediatric cases with hypophosphatasia.
Codes mentioned
C9399J3590
Original notice
Strensiq (asfotase alfa)
bcbsms.com · Always check the source before changing claims.
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