CommercialAdministrativeLow impact
Lacrisert (hydroxypropyl cellulose insert)
Blue Cross & Blue Shield of Mississippi·MS · Ophthalmology, Family Medicine, Internal Medicine·Medical Policy
Effective date
Jun 3, 2025
We identified it
Jun 20, 2026
Summary
BCBS Mississippi updated their Lacrisert (hydroxypropyl cellulose insert) policy with terminology changes from 'pellet' to 'insert' and clarified that samples cannot be used to meet medical necessity requirements. Prior authorization is still required for this dry eye treatment medication.
Action Required
By June 3, 2025: Billing team should update any internal documentation or prior authorization requests to reference Lacrisert as 'hydroxypropyl cellulose insert' instead of 'pellet'. Ensure prior authorization is obtained before prescribing and remind providers that sample usage cannot satisfy medical necessity requirements.