All PlansCoverageMedium impact
High Sensitivity C-Reactive Protein (CRP)
Blue Cross & Blue Shield of Mississippi·MS · Cardiology, Internal Medicine, Family Medicine·Medical Policy
We identified it
Jun 20, 2026
Summary
This policy confirms that High Sensitivity C-Reactive Protein (hs-CRP) testing remains classified as investigational and is not covered, including its use for cardiovascular disease risk assessment. The policy was reviewed but no changes were made to the coverage determination.
Action Required
Immediately: Billing team should verify that CPT 86141 (High Sensitivity C-Reactive Protein) is flagged as non-covered/investigational in billing system. Ensure claims are not submitted for this test as they will be denied. Providers should be informed that hs-CRP testing for cardiovascular risk assessment is not covered by this payer.