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Genetic Testing for Lipoprotein(a) Variant(s) as a Decision Aid for Aspirin Treatment

Blue Cross & Blue Shield of Mississippi·Cardiology, Family Medicine, Internal Medicine·Medical Policy
Effective date
Not stated
We identified it
Jun 20, 2026
Days to comply

Summary

This policy establishes that genetic testing for the LPA rs3798220 allele (LPA-Aspirin Genotype) to guide aspirin treatment decisions is considered investigational and not covered. The policy clarifies that this testing should not be billed as a covered service.

Action Required

Action needed
Immediately: Billing team should verify that genetic testing for LPA rs3798220 allele (LPA-Aspirin Genotype) is not being billed as a covered service. If any claims are being submitted for this testing, inform providers that it is considered investigational and will be denied. Update billing system notes to flag this as non-covered investigational testing.

Affected Billing Codes

81599