All PlansCoverageMedium impact
Multicancer Early Detection Testing
Blue Cross & Blue Shield of Mississippi·MS · Oncology, Family Medicine, Internal Medicine +1 more·Medical Policy
Effective date
Mar 15, 2024
We identified it
Jun 20, 2026
Summary
This is a new medical policy establishing that multicancer early detection (MCED) tests like Galleri are considered investigational and not covered for cancer screening. The policy clarifies that these blood-based tests that screen for multiple cancers simultaneously are not yet approved by the FDA and lack sufficient evidence for coverage.
Action Required
Immediately: Billing team must deny coverage and inform patients that MCED tests (including Galleri) are considered investigational and not covered by insurance. Use CPT code 81479 (Unlisted molecular pathology procedure) for billing purposes but expect denials. Update encounter forms to note investigational status. Advise patients these tests are out-of-pocket expenses.