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State and School Employees' Health Insurance Plan - Revcovi (elapegademase-lvlr)

Blue Cross & Blue Shield of Mississippi·MS · Hematology, Allergy & Immunology, Oncology +1 more·Medical Policy
Effective date
Sep 1, 2025
We identified it
Jun 20, 2026
Days to comply

Summary

New medical policy added for Revcovi (elapegademase-lvlr), a medication for treating ADA-SCID, a rare genetic immune deficiency. The policy establishes strict prior authorization criteria requiring genetic testing confirmation, specialist prescriber, and excludes patients with severe thrombocytopenia.

Action Required

Action needed
By September 1, 2025: Billing team must implement prior authorization requirements for Revcovi (elapegademase-lvlr) using HCPCS J3590. Ensure specialist prescribers (immunologists, hematologist/oncologists) document ADA-SCID diagnosis with genetic testing results, platelet counts >50×109/L, and absence of FDA contraindications. Claims without proper prior authorization will be denied.

Affected Billing Codes

J3590