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Blue Cross & Blue Shield of MississippiAll Plans · Coverage · Medical Policy · Oncology, RadiologyMedium impact

Transcatheter Arterial Chemoembolization to Treat Primary or Metastatic Liver Malignancies

Effective date
Not stated in the notice
Identified
Jun 20, 2026

Summary

Transcatheter arterial chemoembolization of the liver may be considered medically necessary to treat unresectable hepatocellular cancer confined to the liver, as a bridge to transplant, to treat symptomatic liver metastases from neuroendocrine tumors that persist despite systemic therapy, and to treat liver-dominant metastatic uveal melanoma. It is considered investigational as neoadjuvant or adjuvant therapy for resectable hepatocellular cancer, as part of combination therapy with radiofrequency ablation, for unresectable intrahepatic cholangiocarcinoma, and for other liver metastases or hepatocellular cancer not meeting the criteria above. The policy history records a 09/12/2025 review with no changes.

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What to do

Action · 4 steps
01Billing team: Hepatocellular cancer must be unresectable, confined to the liver, not associated with portal vein thrombosis, and have liver function not characterized as Child-Pugh class C.
02For bridge to transplant, the candidate should have a single tumor less than 5 cm or no more than three tumors each less than 3 cm, absence of extrahepatic disease or vascular invasion, and Child-Pugh class A or B.
03Investigational uses are not considered medically necessary.
04BCBSMS makes no payment for services that are not documented to be Medically Necessary.

Codes mentioned

3724375894Q0083C22.0C22.9C24.0C24.9C78.7

Original notice

Transcatheter Arterial Chemoembolization to Treat Primary or Metastatic Liver Malignancies
bcbsms.com · Always check the source before changing claims.
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