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Blue Cross & Blue Shield of MississippiAll Plans · Coverage · Medical Policy · Oncology, RadiologyMedium impact

Radiofrequency Ablation of Primary or Metastatic Liver Tumors

Effective date
Not stated in the notice
Identified
Jun 20, 2026

Summary

Radiofrequency ablation of inoperable hepatocellular carcinoma may be considered medically necessary as a primary treatment when the tumor meets the Milan criteria (a single tumor of 5 cm or less, or up to 3 nodules under 3 cm), and as a bridge to liver transplant when the intent is to prevent further tumor growth and maintain candidacy for transplant. For inoperable hepatic metastases, it may be considered medically necessary when the metastases are of colorectal origin and meet the Milan criteria, or of neuroendocrine origin and systemic therapy has failed to control symptoms. Ablation of operable hepatocellular carcinoma, of more than three nodules or when not all tumor foci can be adequately treated, of hepatocellular carcinoma used to downstage for transplant, and of hepatic metastases from other cancers except colorectal or neuroendocrine tumors is considered investigational.

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What to do

Action · 4 steps
01Billing team: Bill the ablation codes 47370 (laparoscopic), 47380 (open) or 47382 (percutaneous) only for the indications the policy lists as medically necessary.
02Billing team: Use 76940 for imaging guidance, and 77013 or 77022 for imaging guidance and monitoring, as the code reference describes.
03Billing team: Confirm the medical record documents the Milan criteria (tumor size or nodule count), the bridge-to-transplant intent, or, for neuroendocrine metastases, that systemic therapy has failed to control symptoms, and check the diagnosis codes C22.0, C22.9, C78.7 and C7B.02 against that documentation before submitting.
04Billing team: Ablation outside these indications is considered investigational.

Codes mentioned

473704738047382769407701377022C22.0C22.9C78.7

Original notice

Radiofrequency Ablation of Primary or Metastatic Liver Tumors
bcbsms.com · Always check the source before changing claims.
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