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Genetic Testing for Diagnosis and Management of Mental Health Conditions
Blue Cross & Blue Shield of Mississippi·Psychiatry, Family Medicine, Internal Medicine·Medical Policy
Effective date
Oct 1, 2024
We identified it
Jun 20, 2026
Summary
Genetic testing for mental health conditions and medication management remains investigational and non-covered for all indications. New CPT codes 0476U and 0477U were added to the investigational codes list, effective October 1, 2024.
Action Required
Immediately: Billing team must ensure CPT codes 0476U and 0477U are flagged as investigational/non-covered in billing system. Verify all genetic testing codes for mental health conditions (0173U, 0175U, 0291U, 0292U, 0293U, 0345U, 0392U, 0411U, 0419U, 0423U, 0437U, 0476U, 0477U, 0618U, 0622U, 0627U) are set to deny automatically as these services are considered investigational and will not be covered.