CommercialPrior AuthMedium impact
State and School Employees' Health Insurance Plan - Multiple Sclerosis
Blue Cross & Blue Shield of Mississippi·MS · Neurology·Medical Policy
Effective date
Oct 1, 2025
We identified it
Jun 20, 2026
Summary
Blue Cross Blue Shield of Mississippi updated their Multiple Sclerosis policy to add two new drugs (Briumvi and Ocrevus Zunovo) and clarified that drug samples cannot be used to satisfy medical policy requirements. The policy also updated prior authorization criteria for MS medications including stricter prescriber requirements and specific failure criteria for different drugs.
Action Required
By October 1, 2025: Update prior authorization processes for MS medications to include new drugs Briumvi (ublituximab-xiiy) and Ocrevus Zunovo. Ensure prescribers document that patients cannot use drug samples to satisfy therapy requirements. Update prior auth forms to capture required medication failure documentation and specialist consultation requirements. Train staff that Briumvi is considered not medically necessary and claims will be denied.