CommercialPrior AuthMedium impact
Savella (milnacipran)
Blue Cross & Blue Shield of Mississippi·MS · Rheumatology, Neurology, Pain Management +2 more·Medical Policy
We identified it
Jun 20, 2026
Summary
BCBS Mississippi updated their prior authorization policy for Savella (milnacipran) used to treat fibromyalgia. The policy requires patients to fail at least three specific medications AND pregabalin before Savella can be approved, with strict documentation requirements for medication trials.
Action Required
Immediately: Billing team must verify prior authorization is obtained before prescribing Savella (milnacipran) for fibromyalgia patients. Providers must document failure of at least 3 medications (gabapentin, pramipexole, tricyclic antidepressants, muscle relaxants, or SSRI/SNRI) AND failure of pregabalin up to 450mg/day. Update EMR templates to include medication trial documentation checklist. Claims for Savella without proper prior auth will be denied.