MedicaidAdministrativeLow impact
20-001 Be Aware of Opioid Potentiator Medications
Health Net·CA · Pain Management, Family Medicine, Internal Medicine +3 more·Pharmacy
We identified it
Jun 20, 2026
Summary
Health Net issued guidance alerting providers about medications that enhance opioid effects and increase risks of respiratory depression, coma, and death. This is educational information to help prevent opioid misuse, not a billing or coverage change.
Action Required
Immediately: Providers should review the opioid potentiator medication list when prescribing opioids and consider drug interactions. Clinical staff should add awareness of these drug combinations (benzodiazepines, antihistamines, muscle relaxants, gabapentinoids, etc.) to prescribing protocols. No billing system changes required.