MedicaidAdministrativeLow impact
20-003 Be Aware of Opioid Potentiator Medications
Health Net·CA · Pain Management, General Practice, Neurology +5 more·Pharmacy
We identified it
Jun 20, 2026
Summary
Health Net issued an educational policy alerting providers about medications that enhance opioid effects and increase risks of respiratory depression, coma, and death. This is informational guidance to help prevent opioid misuse, not a billing or coverage change.
Action Required
Immediately: Providers should review the list of opioid potentiator medications (benzodiazepines, antihistamines, antipsychotics, muscle relaxants, gabapentinoids, etc.) and consider drug interactions when prescribing opioids. Share this reference guide with prescribing physicians for clinical decision-making to improve patient safety.