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25-1202m Opioid Interactions: Potentiator Drugs That Increase the Risk of Overdose
Health Net·CA · Pain Management, Family Medicine, Internal Medicine +3 more·Provider News
Effective date
Nov 21, 2025
We identified it
Jun 20, 2026
Summary
HealthNet California has issued a provider alert about opioid drug interactions, specifically highlighting potentiator drugs that can increase overdose risk when combined with opioids. This is an educational resource for providers to understand dangerous medication combinations.
Action Required
Download and review the opioid interaction flyer from HealthNet's provider library. Clinical staff should familiarize themselves with potentiator drugs that increase opioid overdose risk when prescribing or reviewing patient medications.