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Excellus BlueCross BlueShieldCommercial · Coverage · Urinary System (Genitourinary) · NY · Urology, OB-GYN, GastroenterologyMedium impact

Bulking Agents for Treatment of Urinary or Fecal Incontinence 7.01.22

Effective date
Mar 19, 2026
Identified
Jun 20, 2026

Summary

Urethral bulking agents may be considered medically appropriate for urinary incontinence when they are FDA-approved and the indication criteria are met. Collagen implants are covered for stress incontinence due to urethral sphincter dysfunction that is unresponsive to conservative therapy, with a listed indication such as congenital or acquired sphincter weakness or biological female patients with abdominal leak point pressure of 100 cm H2O or less. Bulking agents are covered for stress incontinence due to intrinsic sphincter deficiency only in biological female patients unresponsive to conservative therapy. Urethral bulking agents are not medically necessary for urinary retention with overflow incontinence, ectopic ureter, neurogenic bladder dysfunction, urinary fistulas, or psychogenic incontinence. Perianal bulking agents for fecal incontinence are investigational.

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What to do

Action · 7 steps
01Requirements for billing these services: Bulking agents for stress incontinence due to intrinsic sphincter deficiency must meet all criteria: stress incontinence due to intrinsic sphincter deficiency, biological female patient, and unresponsive to conservative therapy.
02Durasphere use is restricted to prescription use by doctors trained in cystoscope use who have completed the appropriate implant training program.
03Additional Durasphere implants are not medically necessary when incontinence does not improve with five separate injection sessions.
04Bulking agents are FDA-approved only for urinary stress incontinence due to intrinsic sphincter deficiency, and Durasphere, Coaptite, Bulkamid, and Macroplastique are approved only for use in biological females.
05Polytetrafluoroethylene (Teflon), autologous cellular therapy (for example myoblasts or adipose-derived stem cells), and Microballoons (UroVive) are investigational for urinary stress incontinence.
06Autologous muscle cell therapy codes 0999T, 1000T, and 1001T are investigational (E/I).
07CPT 46999 is investigational when used for fecal incontinence (ICD-10 range R15.0-R15.9), and HCPCS L8604 and L8605 are investigational.

Codes mentioned

4699951715L8603L8604L8605L8606N39.3N39.498R32.0

Original notice

Bulking Agents for Treatment of Urinary or Fecal Incontinence 7.01.22
excellusbcbs.com · Always check the source before changing claims.
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